H6878
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H6878
Sigma-Aldrich
8-Hydroxyquinoline
crystalline
| Synonym: | 8-Hydroxyquinoline, 8-Oxychinolin, 8-Quinolinol, Oxine |
| CAS Number: | 148-24-3 |
| Linear Formula: | C9H7NO |
| Molecular Weight: | 145.16 |
| Beilstein Registry Number: | 114512 |
| EC Number: | 205-711-1 |
| MDL number: | MFCD00006807 |
| PubChem Substance ID: | 24895771 |
Description
| Biochem/physiol Actions | RNA synthesis inhibitor that acts as a fungicide against Trichophyton mentagrophytes, Myrothecium verrucaria, and Trichoderma viride. The antifungal mechanism of action is not clear but appears to be structurally related. |
Properties
| form | crystalline |
| color | light yellow |
| bp | 267 °C/752 mmHg(lit.) |
| mp | 70-73 °C(lit.) |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
| RTECS | VC4200000 |
References
| reference | Gershon, H., and Parmegiani, R., Antimicrobial activity of 8-quinolinol, its salts with salicylic acid and 3-hydroxy-2-naphthoic acid, and the respective copper (II) chelates in liquid culture. Appl. Microbiol. 11, 62-5, (1963) Abstract |
| Gershon, H., et al., Evidence of steric factors in the fungitoxic mechanisms of 8-quinolinol and its 5- and 7-halogenated analogues. J. Pharm. Sci. 80, 542-4, (1991) Abstract | |
| Merck | Merck 13,4869 |
| Beilstein | Beil. 21,V,3,252 |
